ERK 1 Monoclonal Antibody, 50ul Cell Function Analysis Several alternatively spliced transcript variants

Several alternatively spliced transcript variants that encode different protein isoforms have been described for this gene

a protein important for DNA double-strand break repair and homologous recombination

the N-terminal regulatory domain that is processed upon calpain activation

heme A: farnesyltransferase cytochrome c oxidase assembly factor is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane

ERK 1 Monoclonal Antibody, 50ul Cell Function Analysis Several alternatively spliced transcript variantsThe protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear