MED28 Polyclonal Antibody, 50ul Cell Screening and Imaging CENPA encodes a centromere protein

CENPA encodes a centromere protein which contains a histone H3 related histone fold domain that is required for targeting to the centromere

interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation

Highest level in lung

Phosphorylates RS domain-containing proteins

MED28 Polyclonal Antibody, 50ul Cell Screening and Imaging CENPA encodes a centromere proteinComponent of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II dependent genes. Mediator functions as a bridge to convey information from gene specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with