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Wee1(Phospho Ser642) Polyclonal Antibody, 20ul Cell Labeling & Imaging Although differing in substrate specificity|

SKU: 65156058932

4.1
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Wee1(Phospho Ser642) Polyclonal Antibody, 20ul Cell Labeling & Imaging Although differing in substrate specificity|This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2 cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

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Description

Although differing in substrate specificity| subcellular localization| and tissue distribution| all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters| and thereby play a key role in lipid biosynthesis and fatty acid degradation

which has led to the suggestion that the encoded protein may function to limit the signaling range of the TGF-beta family during early embryogenesis

Polymorphisms in this gene may increase the risk of getting certain cancers

It regulates the uptake of chemically modified low density lipoproteins

Wee1(Phospho Ser642) Polyclonal Antibody, 20ul Cell Labeling & Imaging Although differing in substrate specificity|This gene encodes a nuclear protein, which is a tyrosine kinase belonging to the Ser Thr family of protein kinases. This protein catalyzes the inhibitory tyrosine phosphorylation of CDC2 cyclin B kinase, and appears to coordinate the transition between DNA replication and mitosis by protecting the nucleus from cytoplasmically activated CDC2 kinase.

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