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Trk A Polyclonal Antibody, 100ul[BT-AP09212] Cell Biology This gene is part of

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Trk A Polyclonal Antibody, 100ul[BT-AP09212] Cell Biology This gene is part ofNTRK1 encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self mutilating behavior,

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Description

This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21

A related pseudogene has been identified on chromosome 13

It encodes a protein which is highly similar to the viral protein

GSTT1 and GSTT2/GSTT2B share 55% amino acid sequence identity and may play a role in human carcinogenesis

Trk A Polyclonal Antibody, 100ul[BT-AP09212] Cell Biology This gene is part ofNTRK1 encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self mutilating behavior,

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