CREB5 Rabbit Polyclonal Antibody, 50ul Rotator The gene product contains an

The gene product contains an N-terminal DNA binding domain and C-terminal ligand binding domain and is localized to the nucleus

The protein is an important drug target for the treatment of type 2 diabetes and stroke

Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome

A related protein in mouse suggests that this protein (armadillo repeat containing 6) has a conserved function

CREB5 Rabbit Polyclonal Antibody, 50ul Rotator The gene product contains anThe product of this gene belongs to the CRE (cAMP response element) binding protein family. Members of this family contain zinc finger and bZIP DNA binding domains. The encoded protein specifically binds to CRE as a homodimer or a heterodimer with c Jun or CRE BP1 and functions as a CRE dependent trans activator. Alternatively spliced transcript variants encoding different isoforms have been identified.