CD63 Polyclonal Antibody, 100ul[BT-AP01878] Culture Media Mutations in BTK cause X-linked

Mutations in BTK cause X-linked agammaglobulinemia type 1

Mice homozygous for this mutation die shortly after birth from massive loss of mid- and hindbrain neurons during late embryogenesis

May act as a receptor in regulating T-cell proliferation

and mediate the signal transduction that leads to the activation of NF-kappaB

CD63 Polyclonal Antibody, 100ul[BT-AP01878] Culture Media Mutations in BTK cause X-linkedACAN is a member of the aggrecan versican proteoglycan family. Aggrecan core protein is an integral part of the extracellular matrix in cartilagenous tissue and it withstands compression in cartilage. Mutations in this gene may be involved in skeletal dysplasia and spinal degeneration. Multiple alternatively spliced transcript variants that encode different protein isoforms have been observed in this gene.