HIRA Polyclonal Antibody, 50ul Stepper |Belongs to the replication factor

|Belongs to the replication factor A protein 1 family

characterized by the signature 7-transmembrane domain motif

and interleukin-1 receptor antagonist

Three transcript variants encoding different isoforms have been found for AKR1C3

HIRA Polyclonal Antibody, 50ul Stepper |Belongs to the replication factorHIRA (histone cell cycle regulator) encodes a histone chaperone that preferentially places the variant histone H3. in nucleosomes. Orthologs of HIRA in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is