FKB11 Rabbit Polyclonal Antibody, 100ul Site-directed Mutagenesis Binds to GC box promoters

Binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites

This gene is expressed primarily in B-lymphoid and myeloid cell lines

This gene encodes a bromodomain-containing protein that localizes to the nucleus and can interact with DNA and histone tails

and CDK8 that can negatively regulate transactivation by mediator

FKB11 Rabbit Polyclonal Antibody, 100ul Site-directed Mutagenesis Binds to GC box promotersFKBP11 belongs to the FKBP family of peptidyl prolyl cis trans isomerases which catalyze the folding of proline containing polypeptides. The peptidyl prolyl isomerase activity of FKBP proteins is inhibited by the immunosuppressant compounds FK506 and rapamycin (Rulten et al. 2006