Amphiphysin I Polyclonal Antibody, 50ul Culture Plate Inserts POM121 (POM121 transmembrane nucleoporin) encodes

POM121 (POM121 transmembrane nucleoporin) encodes a transmembrane protein that localizes to the inner nuclear membrane and forms a core component of the nuclear pore complex

Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma

Proteolytic processing of this type XI chain produces PARP

PTM:Undergoes a tyrosination/detyrosination cycle

Amphiphysin I Polyclonal Antibody, 50ul Culture Plate Inserts POM121 (POM121 transmembrane nucleoporin) encodesAMPH encodes a protein (amphiphysin) associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of