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IP Receptor Polyclonal Antibody, 50ul Protein Expression In humans| polymorphisms in this

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IP Receptor Polyclonal Antibody, 50ul Protein Expression In humans| polymorphisms in thisThe protein encoded by PTGIR (prostaglandin I2 (prostacyclin) receptor (IP)) is a member of the G protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.

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Description

In humans| polymorphisms in this gene are associated with variation in human height and osteoarthritis

The protein contains C2 domains that play a role in calcium-mediated membrane fusion events| suggesting that it may be involved in membrane regeneration and repair

and they are activated by binding GTP and inactivated by conversion of GTP to GDP by their intrinsic GTPase activity

This protein binds activated forms of Rho GTPases and stimulates GTP hydrolysis

IP Receptor Polyclonal Antibody, 50ul Protein Expression In humans| polymorphisms in thisThe protein encoded by PTGIR (prostaglandin I2 (prostacyclin) receptor (IP)) is a member of the G protein coupled receptor family 1 and has been shown to be a receptor for prostacyclin. Prostacyclin, the major product of cyclooxygenase in macrovascular endothelium, elicits a potent vasodilation and inhibition of platelet aggregation through binding to this receptor.

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