Rat Nephrin, NPHN ELISA Kit, 96T Yeast Expression Allelic variants of this gene

Allelic variants of this gene are associated with generalized epilepsy with febrile seizures and epileptic encephalopathy

cleaves SPHK2 which is released from cells and remains enzymatically active extracellularly

thereby inhibiting their ability to induce T cell activation (By similarity)

It also plays a role in nuclear pre-mRNA retention and transcriptional repression

Rat Nephrin, NPHN ELISA Kit, 96T Yeast Expression Allelic variants of this geneSeems to play a role in the development or function of the kidney glomerular filtration barrier. Regulates glomerular vascular permeability. May anchor the podocyte slit diaphragm to the actin cytoskeleton. Plays a role in skeletal muscle formation through regulation of myoblast fusion.