PERK Monoclonal Antibody, 100ul In vitro Assessment May be a transcriptional repressor

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PERK Monoclonal Antibody, 100ul In vitro Assessment May be a transcriptional repressorThe protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in

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