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p21 Polyclonal Antibody, 20ul[BT-AP12602] Pipette Holder CSNK1G1 (casein kinase 1 gamma

SKU: 67727089393

4.1
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p21 Polyclonal Antibody, 20ul[BT-AP12602] Pipette Holder CSNK1G1 (casein kinase 1 gammaThis gene encodes a potent cyclin dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin cyclin dependent kinase2 or cyclin dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53 dependent cell cycle G1 phase arrest in response to a variety of

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Description

CSNK1G1 (casein kinase 1 gamma 1) encodes a member of the casein kinase I gene family

Alternative splicing of TP63 and the use of alternative promoters results in multiple transcript variants encoding different isoforms that vary in their functional properties

This protein also plays a central role in DNA damage repair

with translation initiation from the upstream start codon allowing for transport to the mitochondria and translation initiation from a downstream start codon allowing for transport to the nucleus

p21 Polyclonal Antibody, 20ul[BT-AP12602] Pipette Holder CSNK1G1 (casein kinase 1 gammaThis gene encodes a potent cyclin dependent kinase inhibitor. The encoded protein binds to and inhibits the activity of cyclin cyclin dependent kinase2 or cyclin dependent kinase4 complexes, and thus functions as a regulator of cell cycle progression at G1. The expression of this gene is tightly controlled by the tumor suppressor protein p53, through which this protein mediates the p53 dependent cell cycle G1 phase arrest in response to a variety of

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