RhoGEF p115 Polyclonal Antibody, 100ul Enzyme Activity Assays Ligand-binding lead to activation of

Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1)

which are induced by various agonists such as the phorbol ester TPA and the polypeptide mitogen EGF

This protein maintains the structural integrity of inner ear hair cells and mutations in this gene cause non-syndromic autosomal dominant and recessive hearing loss

pneumoniae and C

RhoGEF p115 Polyclonal Antibody, 100ul Enzyme Activity Assays Ligand-binding lead to activation ofRho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The rho guanine nucleotide exchange factor 1 may form complex with G proteins and stimulate Rho dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full length nature of some variants has not been defined.