Bovine Insulin-like Growth Factor Binding Protein 5, IGFBP5 ELISA Kit , 96T Bottle-Top Dispenser Four different regulatory subunits and

Four different regulatory subunits and three catalytic subunits have been identified in humans

The protein encoded by this gene is an inner protein of the kinetochore

Dysregulation of this gene has been associated with the growth and progression of certain cancers

Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis

Bovine Insulin-like Growth Factor Binding Protein 5, IGFBP5 ELISA Kit , 96T Bottle-Top Dispenser Four different regulatory subunits andIGF binding proteins prolong the half life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.