ALPP/ALPPL2 Polyclonal Antibody, 100ul Pipette Controller Alternative splicing results in a

Alternative splicing results in a multitude of transcript variants

The encoded protein is expressed predominantly in endothelial cells of capillaries as well as larger vessels of the placenta where it may mediate the inhibitory effect of angiostatin on tube formation and the migration of endothelial cells toward growth factors during the formation of new blood vessels

|disease:Defects in ACAN are the cause of spondyloepiphyseal dysplasia type Kimberley (SEDK)

Telomerase expression plays a role in cellular senescence

ALPP/ALPPL2 Polyclonal Antibody, 100ul Pipette Controller Alternative splicing results in aAlkaline phosphatase, placental type encoded by ALPP is an alkaline phosphatase, a metalloenzyme that catalyzes the hydrolysis of phosphoric acid monoesters. It belongs to a multigene family composed of four alkaline phosphatase isoenzymes. The enzyme functions as a homodimer and has a catalytic site containing one magnesium and two zinc ions, which are required for its enzymatic function. The protein is primarily expressed in placental and