p53(Phospho Ser315) Polyclonal Antibody, 50ul Vortex Mixer Alternatively spliced transcript variants encoding
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p53(Phospho Ser315) Polyclonal Antibody, 50ul Vortex Mixer Alternatively spliced transcript variants encodingThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.
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