ACTR-IC Polyclonal Antibody, 50ul Pipette Controller This protein is a member

This protein is a member of the ALD subfamily| which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle

In collagen and related proteins| prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains

Variations in this gene may be associated with susceptibility to systemic lupus erythematosus (SLE)

The product of this gene contains multiple epidermal growth factor (EGF)-like and LamG domains

ACTR-IC Polyclonal Antibody, 50ul Pipette Controller This protein is a memberACVR1C is a type I receptor for the TGFB (see MIM 190180) family of signaling molecules. Upon ligand binding, type I receptors phosphorylate cytoplasmic SMAD transcription factors, which then translocate to the nucleus and interact directly with DNA or in complex with other transcription factors (Bondestam et al. 2001 [PubMed 12063393]).