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DAB2 Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification A pseudogene of this gene

SKU: 7032490295

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DAB2 Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification A pseudogene of this geneThis gene encodes a mitogen responsive phosphoprotein. It is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2 an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras) via its C terminal proline rich sequences and may thus modulate growth factor Ras

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Description

A pseudogene of this gene is located on the long arm of chromosome 7

and being expressed in vascular endothelium cells and binding to L-selectin

Alström syndrome

This protein functions as a receptor for bile acids

DAB2 Rabbit Polyclonal Antibody, 100ul Protein Post-translational Modification A pseudogene of this geneThis gene encodes a mitogen responsive phosphoprotein. It is expressed in normal ovarian epithelial cells but is down regulated or absent from ovarian carcinoma cell lines suggesting its role as a tumor suppressor. This protein binds to the SH3 domains of GRB2 an adaptor protein that couples tyrosine kinase receptors to SOS (a guanine nucleotide exchange factor for Ras) via its C terminal proline rich sequences and may thus modulate growth factor Ras

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