Dok-3 Polyclonal Antibody, 20ul Electrophoresis & Labeling These peptides act as autocrine
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Dok-3 Polyclonal Antibody, 20ul Electrophoresis & Labeling These peptides act as autocrineDok 1, Dok 2 and Dok 3 are members of a class of "docking" proteins which contain multiple tyrosine residues and putative SH2 binding sites. Dok 1 associates with the Ras GTPase activating protein (Ras GAP) upon tyrosine phosphorylation. Dok 2 (also designated p56 Dok) has also been identified as a potential mediator of the effects of p210 Bcr Abl. Dok 3 is an adapter involved in the recruitment of inhibitory molecules and is highly expressed in B
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