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Mouse Integrin Alpha-2B, ITGA2B ELISA Kit, 96T Digital Burette Required during early development to

SKU: 70762125560

4.2
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Mouse Integrin Alpha-2B, ITGA2B ELISA Kit, 96T Digital Burette Required during early development toIntegrin alpha 2 beta 1 is a collagen receptor, being responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. It is also a receptor for laminins, collagen C propeptides and E cadherin. Mice homozygous for a null mutation in the alpha 2 die very early in embryogenesis.

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Description

Required during early development to promote gastrulation: acts by mediating O-glucosylation of CRB2

Catalyzes sulfoxidation of the anthelmintics albendazole and fenbendazole (PubMed: 10759686)

Binds to and enhances the translation of mRNAs for several metabolic enzymes

permitting endocytosis

Mouse Integrin Alpha-2B, ITGA2B ELISA Kit, 96T Digital Burette Required during early development toIntegrin alpha 2 beta 1 is a collagen receptor, being responsible for adhesion of platelets and other cells to collagens, modulation of collagen and collagenase gene expression, force generation and organization of newly synthesized extracellular matrix. It is also a receptor for laminins, collagen C propeptides and E cadherin. Mice homozygous for a null mutation in the alpha 2 die very early in embryogenesis.

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