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Histone H3 (Mono Methyl Lys79) Monoclonal Antibody(1C2), 20ul Cell Labeling & Imaging Suppressor of cytokine signaling 2

SKU: 70842030293

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Histone H3 (Mono Methyl Lys79) Monoclonal Antibody(1C2), 20ul Cell Labeling & Imaging Suppressor of cytokine signaling 2Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin

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Description

Suppressor of cytokine signaling 2 encoded by SOCS2 interacts with the cytoplasmic domain of insulin-like growth factor-1 receptor (IGF1R) and is thought to be involved in the regulation of IGF1R mediated cell signaling

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member of RAS oncogene family-like 2A in the family of RAS-related signaling molecules are small GTP-binding proteins that play important roles in the regulation of exocytotic and endocytotic pathways

A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases

Histone H3 (Mono Methyl Lys79) Monoclonal Antibody(1C2), 20ul Cell Labeling & Imaging Suppressor of cytokine signaling 2Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. This structure consists of approximately 146 bp of DNA wrapped around a nucleosome, an octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin

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