NARF Polyclonal Antibody, 100ul Plates & Dishes Several alternatively spliced transcripts encoding

Several alternatively spliced transcripts encoding two different isoforms have been described

The antigen is being used as a target for immunotherapy treatment of human carcinomas

PGC (progastricsin) encodes an aspartic proteinase that belongs to the peptidase family A1

Component of the SCF(FBXW11) complex containing FBXW11

NARF Polyclonal Antibody, 100ul Plates & Dishes Several alternatively spliced transcripts encodingSeveral proteins have been found to be prenylated and methylated at their carboxyl terminal ends. Prenylation was initially believed to be important only for membrane attachment. However, another role for prenylation appears to be its importance in protein protein interactions. The only nuclear proteins known to be prenylated in mammalian cells are prelamin A and B type lamins. Prelamin A is farnesylated and carboxymethylated on the cysteine residue