INGR2 Polyclonal Antibody, 20ul Inoculating Loops/Needles |PTM:Phosphorylated in the C-terminal upon

|PTM:Phosphorylated in the C-terminal upon stimulation by nerve growth factor (NGF) and epidermal growth factor (EGF)

This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation

|tissue specificity:Detected in spleen and thyroid| and at lower levels in kidney| brain| lung and pancreas

and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules

INGR2 Polyclonal Antibody, 20ul Inoculating Loops/Needles |PTM:Phosphorylated in the C-terminal uponThis gene (IFNGR2) encodes the non ligand binding beta chain of the gamma interferon receptor. Human interferon gamma receptor is a heterodimer of IFNGR1 and IFNGR2. Defects in IFNGR2 are a cause of mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. MSMD is a genetically heterogeneous disease with autosomal recessive, autosomal dominant or X linked inheritance.