ADAM10 Polyclonal Antibody, 50ul PCR Series Constitutive activation of this gene

Constitutive activation of this gene caused either by somatic mutations

Mutations in ROR2 can cause brachydactyly type B

elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport

a putative tumor suppressor associated with a syndrome known as multiple endocrine neoplasia type 1

ADAM10 Polyclonal Antibody, 50ul PCR Series Constitutive activation of this geneMembers of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. ADAM10 encodes and ADAM family member that cleaves many proteins including TNF alpha and E cadherin. Alternate splicing results in multiple transcript variants encoding different proteins that may undergo similar processing.