FCN2 Polyclonal Antibody, 20ul Monoclonal Antibodies Upon binding| this complex translocates

Upon binding| this complex translocates to the cytoplasm| where it interacts with TGF-beta receptor type-1 (TGFBR1)| leading to the degradation of both the encoded protein and TGFBR1

The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide

or N-acetylglucosamine (GlcNAc) residues within proteoglycans

An important paralog of this gene is FOXE3

FCN2 Polyclonal Antibody, 20ul Monoclonal Antibodies Upon binding| this complex translocatesThe product of this gene belongs to the ficolin family of proteins. This family is characterized by the presence of a leader peptide, a short N terminal segment, followed by a collagen like region, and a C terminal fibrinogen like domain. This gene is predominantly expressed in the liver, and has been shown to have carbohydrate binding and opsonic activities. Alternatively spliced transcript variants encoding different isoforms have been identified.