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p53R2 Polyclonal Antibody, 100ul Vessels thyroid-associated orbitopathy

SKU: 71732105705

4.7
EUR141.00 EUR164.00

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p53R2 Polyclonal Antibody, 100ul Vessels thyroid-associated orbitopathyRRM2B encodes the small subunit of a p53 inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in RRM2B have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia 5, and mitochondrial

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Description

thyroid-associated orbitopathy

may play a role in the mucosal/epithelial immune response and epidermal differentiation

This gene is located in an intron of the FBXL13 gene on the opposite strand

The encoded protein is cadherin-like

p53R2 Polyclonal Antibody, 100ul Vessels thyroid-associated orbitopathyRRM2B encodes the small subunit of a p53 inducible ribonucleotide reductase. This heterotetrameric enzyme catalyzes the conversion of ribonucleoside diphosphates to deoxyribonucleoside diphosphates. The product of this reaction is necessary for DNA synthesis. Mutations in RRM2B have been associated with autosomal recessive mitochondrial DNA depletion syndrome, autosomal dominant progressive external ophthalmoplegia 5, and mitochondrial

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