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Variations in this gene have been linked to metabolic syndrome

while the HLH domain facilitates the mono- and heterodimeric interactions required for efficient DNA binding

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Oct-3/4 Polyclonal Antibody, 100ul[BT-AP06332] Capsule Filter Get precise and reliable resultsPOU5F1 (POU class 5 homeobox 1) encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of POU5F1 in adult tissues is associated with tumorigenesis. POU5F1 can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG