Human Profilin 1 ELISA Kit, 96T Gene Synthesis PubMed: 11882383

PubMed: 11882383

TICAM1 (toll like receptor adaptor molecule 1) encodes an adaptor protein containing a Toll/interleukin-1 receptor(TIR) homology domain

A HECT (homology to E6-AP C-terminus) domain in the C-terminus of the longer isoform of this protein is the catalytic site of ubiquitin transfer and forms a complex with E2 conjugases

neuronal differentiation

Human Profilin 1 ELISA Kit, 96T Gene Synthesis PubMed: 11882383Binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG. Inhibits androgen receptor (AR) and HTT aggregation and binding of G actin is essential for its inhibition of AR.