CLSPN Polyclonal Antibody, 50ul Gene Synthesis This gene was initially mapped

This gene was initially mapped to chromosome 14

At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene

A second breast cancer susceptibility gene

These motifs are thought to be involved in ATP binding

CLSPN Polyclonal Antibody, 50ul Gene Synthesis This gene was initially mappedThe product of this gene is an essential upstream regulator of checkpoint kinase 1 and triggers a checkpoint arrest of the cell cycle in response to replicative stress or DNA damage. The protein is also required for efficient DNA replication during a normal S phase. Multiple transcript variants encoding different isoforms have been found for this gene.