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CALRL Polyclonal Antibody, 50ul Cell Function Analysis It has been associated with

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CALRL Polyclonal Antibody, 50ul Cell Function Analysis It has been associated withReceptor for calcitonin gene related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3 (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,Belongs to the G protein coupled receptor 2 family.,subunit: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.,tissue specificity: Predominantly expressed in the lung and heart.,

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Description

It has been associated with multiple functions| including axon membrane trafficking| axonal homeostasis| mitophagy| adipose differentiation| and hematopoietic stem cell maintenance

Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities

The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells

Radial spokes| which are regularly spaced along cilia| sperm| and flagella axonemes| consist of a thin 'stalk' and a bulbous 'head' that form a signal transduction scaffold between the central pair of microtubules and dynein

CALRL Polyclonal Antibody, 50ul Cell Function Analysis It has been associated withReceptor for calcitonin gene related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3 (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,Belongs to the G protein coupled receptor 2 family.,subunit: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.,tissue specificity: Predominantly expressed in the lung and heart.,

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