Pirh2 Monoclonal Antibody, 100ul Pathway and Network Analysis Alternate splicing generates multiple transcript

Alternate splicing generates multiple transcript variants encoding distinct isoforms

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway

The precise role of this protein is unknown but studies suggest it may play a role in cytoskeletal organization| vesicular transport| or in transcriptional regulation of both nuclear and mitochondrial genes

RPL36 encodes a ribosomal protein that is a component of the 60S subunit

Pirh2 Monoclonal Antibody, 100ul Pathway and Network Analysis Alternate splicing generates multiple transcriptThe protein encoded by this gene has ubiquitin ligase activity. It mediates E3 dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.