TBCD7 Rabbit Polyclonal Antibody, 20ul Endonucleases & Exonucleases The protein encoded by ARHGEF5

The protein encoded by ARHGEF5 (Rho guanine nucleotide exchange factor 5) may form a complex with G proteins and stimulate Rho-dependent signals

It is thought that complexes of lectins and this protein mediate protein folding by promoting formation of disulfide bonds in their glycoprotein substrates

Post-translational modifications decrease the ability to chaperone

craniofacial

TBCD7 Rabbit Polyclonal Antibody, 20ul Endonucleases & Exonucleases The protein encoded by ARHGEF5This gene encodes a member of the TBC domain containing protein family. The encoded protein functions as a subunit of the tuberous sclerosis TSC1 TSC2 complex which plays a role in the regulation of cellular growth and differentiation. Mutations in this gene have been associated with autosomal recessive megalencephaly. Alternative splicing results in multiple transcript variants. Naturally occurring readthrough transcription occurs between this locus