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KIF5C Rabbit Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) Has a role in cardioprotection

SKU: 7381695875

4.8
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KIF5C Rabbit Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) Has a role in cardioprotectionThe protein encoded by this gene is a kinesin heavy chain subunit involved in the transport of cargo within the central nervous system. The encoded protein which acts as a tetramer by associating with another heavy chain and two light chains interacts with protein kinase CK2. Mutations in this gene have been associated with complex cortical dysplasia with other brain malformations 2. Two transcript variants one protein coding and the other non protein

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Description

Has a role in cardioprotection by reducing cardiac hypertrophy and perivascular fibrosis in a RAMP3-dependent manner

Gene mutations that lead to a loss in function are associated with increased pheomelanin production

Alternate splicing results in three transcript variants

RCC2/TD-60 is a member of the RCC1 (regulator of chromosome condensation 1) family of guanine nucleotide exchange factors

KIF5C Rabbit Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) Has a role in cardioprotectionThe protein encoded by this gene is a kinesin heavy chain subunit involved in the transport of cargo within the central nervous system. The encoded protein which acts as a tetramer by associating with another heavy chain and two light chains interacts with protein kinase CK2. Mutations in this gene have been associated with complex cortical dysplasia with other brain malformations 2. Two transcript variants one protein coding and the other non protein

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