DUS14 Polyclonal Antibody, 20ul Enzymes & Activity Assays Phosphorylated derivatives of phosphatidylinositol (PtdIns)

Phosphorylated derivatives of phosphatidylinositol (PtdIns) regulate cytoskeletal functions

has also been classified as a Pc protein [PMID: 14647293]

Alternate splicing results in two transcript variants that encode different proteins

Clusterin encoded by CLU is a secreted chaperone that can under some stress conditions also be found in the cell cytosol

DUS14 Polyclonal Antibody, 20ul Enzymes & Activity Assays Phosphorylated derivatives of phosphatidylinositol (PtdIns)Dual specificity phosphatases (DUSPs) constitute a large heterogeneous subgroup of the type I cysteine based protein tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine threonine residues. They have been implicated as major modulators of critical signaling pathways. DUSP14 contains the consensus DUSP C terminal catalytic domain but lacks the N terminal CH2 domain found in the MKP