DCAMKL2 Polyclonal Antibody, 50ul Serum & Sample Tubes Caspases exist as inactive proenzymes

Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic acid residues to produce two subunits

Belongs to the amino acid-polyamine-organocation (APC) superfamily

and involvement in cargo sorting during receptor endocytosis

It can bind to diacylglycerol (DAG) in the trans-Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN

DCAMKL2 Polyclonal Antibody, 50ul Serum & Sample Tubes Caspases exist as inactive proenzymesDCLK2 encodes a member of the protein kinase superfamily and the doublecortin family. Doublecortin like kinase 2 encoded by DCLK2 contains two N terminal doublecortin domains, which bind microtubules and regulate microtubule polymerization, a C terminal serine threonine protein kinase domain, which shows substantial homology to Ca2+ calmodulin dependent protein kinase, and a serine proline rich domain in between the doublecortin and the protein kinase