Rat Alpha2-Microglobulin, A2-MG ELISA Kit, 96T Diagnostic Probes & Oligos This protein forms part of

This protein forms part of the RNA polymerase II (RNAPII) enzyme complex and may recruit RNAPII to chromatin through its interaction with acetylated histones

PubMed: 21982598)

These chains associate via disulfide linkages to form the heterodimeric enzyme

Transgenic mice in which the beta 2 chain gene was inactivated by homologous recombination

Rat Alpha2-Microglobulin, A2-MG ELISA Kit, 96T Diagnostic Probes & Oligos This protein forms part ofIs able to inhibit all four classes of proteinases by a unique 'trapping' mechanism. This protein has a Peptide stretch, called the 'bait region' which contains specific cleavage sites for different proteinases. When a proteinase cleaves the bait region, a conformational change is induced in the protein which traps the proteinase. The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight