ARHGEF9 Polyclonal Antibody, 100ul Funnels Found in the granular layer

Found in the granular layer of the cerebellum

The protein localizes to the nucleoli and interacts with the U3 snoRNP complex

and five repeat units have been reported

It may instead modulate signal transduction through the beta-arrestin pathway

ARHGEF9 Polyclonal Antibody, 100ul Funnels Found in the granular layerThe Cdc42 guanine nucleotide exchange factor 9 encoded by ARHGEF9 is a Rho like GTPase that switches between the active (GTP bound) state and inactive (GDP bound) state to regulate CDC42 and other genes. Defects in this gene are a cause of startle disease with epilepsy (STHEE), also known as hyperekplexia with epilepsy. Three transcript variants encoding different isoforms have been found for this gene.