NR4A2 Polyclonal Antibody, 50ul Cell Culture Dishes The mitogen-activated protein kinase kinase

The mitogen-activated protein kinase kinase kinase 8 localizes to the cytoplasm and can activate both the MAP kinase and JNK kinase pathways

Alternatively spliced transcript variants that encode different isoforms have been observed for this gene

The encoded preproprotein is proteolytically processed into biologically active C-terminal peptide fragments

This kinase functions preferentially on the JNK signaling pathway

NR4A2 Polyclonal Antibody, 50ul Cell Culture Dishes The mitogen-activated protein kinase kinaseThis gene encodes a member of the steroid thyroid hormone retinoid receptor superfamily. The encoded protein may act as a transcription factor. Mutations in this gene have been associated with disorders related to dopaminergic dysfunction, including Parkinson disease, schizophernia, and manic depression. Misregulation of this gene may be associated with rheumatoid arthritis. Alternatively spliced transcript variants have been described, but their