Phospho-5-LO (S523) Polyclonal Antibody, 100ul Cell Function Analysis The mitochondrially-encoded subunits function in

The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex

VPS37C and VPS28

the C-terminal kinase domain binds to its own N-terminal region

The protein encoded by this gene functions as a receptor or| with Frizzled| a co-receptor for Wnt and thereby transmits the canonical Wnt/beta-catenin signaling cascade

Phospho-5-LO (S523) Polyclonal Antibody, 100ul Cell Function Analysis The mitochondrially-encoded subunits function inALOX5 encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The arachidonate 5 lipoxygenasen, which is expressed specifically in bone marrow derived cells, catalyzes the conversion of arachidonic acid to 5(S) hydroperoxy 6 trans 8,11,14 cis eicosatetraenoic acid, and further to the allylic epoxide 5(S) trans 7,9 trans 11,14 cis eicosatetrenoic acid (leukotriene A4). Leukotrienes