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Diseases associated with SERPINB5 include mandibular cancer and laryngeal carcinoma

The protein is a component of the the PAF protein complex

The encoded protein undergoes an initial autocatalytic processing event in the ER to generate a heterodimer which exits the ER and sorts to subcellular compartments where a second autocatalytic even takes place and the Catalytic activity is acquired

SIRT1 Monoclonal Antibody, 100ul Buffer Solutions never worry about contaminating samplesThis gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular