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IκB-alpha Polyclonal Antibody, 100ul[BT-AP10545] Bio-Reaction Tube Defects in this gene are

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IκB-alpha Polyclonal Antibody, 100ul[BT-AP10545] Bio-Reaction Tube Defects in this gene areThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

Defects in this gene are a cause of Fukuyama-type congenital muscular dystrophy (FCMD)

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This protein also degrades the outer membrane protein A (OmpA) of E

The hypothalamic suprachiasmatic nucleus appears to be involved in circadian rhythm while the hypophysial pars tuberalis may be responsible for the reproductive effects of melatonin

IκB-alpha Polyclonal Antibody, 100ul[BT-AP10545] Bio-Reaction Tube Defects in this gene areThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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