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VHL Polyclonal Antibody, 50ul[BT-AP15472] Antibody Humanization is responsible for the deamination

SKU: 74960648067

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VHL Polyclonal Antibody, 50ul[BT-AP15472] Antibody Humanization is responsible for the deaminationVon Hippel Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin 2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and

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Description

is responsible for the deamination of adenosine 37 to inosine in eukaryotic tRNA

It contains a Sec7 domain

and tumor growth inhibition

Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency

VHL Polyclonal Antibody, 50ul[BT-AP15472] Antibody Humanization is responsible for the deaminationVon Hippel Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin 2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and

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