ST5 Polyclonal Antibody, 50ul Filtration 2003 [PubMed 12837247])

2003 [PubMed 12837247])

The protein encoded by this gene interacts with RhoA within the cell nucleus and may play a role in repairing DNA damage after ionizing radiation

This protein also promotes the nuclear translocation of p120

The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate

ST5 Polyclonal Antibody, 50ul Filtration 2003 [PubMed 12837247])ST5 was identified by its ability to suppress the tumorigenicity of Hela cells in nude mice. Suppression of tumorigenicity 5 protein encoded by ST5 contains a C terminal region that shares similarity with the Rab 3 family of small GTP binding proteins. This protein preferentially binds to the SH3 domain of c Abl kinase, and acts as a regulator of MAPK1 ERK2 kinase, which may contribute to its ability to reduce the tumorigenic phenotype in cells. Three