Akt Polyclonal Antibody, 50ul[BT-AP00339] Lentiviral Packaging Defects in this gene are

Defects in this gene are a cause of chromosome 9q subtelomeric deletion syndrome (9q-syndrome

Mutation in this gene has been associated with Amish infantile epilepsy syndrome

and inhibiting its expression partially suppresses p53-induced apoptosis

The KLHL1 protein belongs to a family of actin-organizing proteins related to Drosophila Kelch (Nemes et al

Akt Polyclonal Antibody, 50ul[BT-AP00339] Lentiviral Packaging Defects in this gene areThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a