Human Serine/Arginine-rich Splicing Factor 1, SFRS1 ELISA Kit , 96T In vitro Transcription CUL-1-mediated ubiquitination results in the

CUL-1-mediated ubiquitination results in the degradation of cell cycle proteins cyclin D

A related protein interacts with calcium/calmodulin-dependent serine protein kinase (CASK)

and function of granulocytes

A similar protein in mouse is required for early development of the embryo

Human Serine/Arginine-rich Splicing Factor 1, SFRS1 ELISA Kit , 96T In vitro Transcription CUL-1-mediated ubiquitination results in thePlays a role in preventing exon skipping, ensuring the accuracy of splicing and regulating alternative splicing. Interacts with other spliceosomal components, via the RS domains, to form a bridge between the 5' and 3' splice site binding components, U1 snRNP and U2AF. Can stimulate binding of U1 snRNP to a 5' splice site containing pre mRNA. Binds to purine rich RNA sequences, either the octamer, 5' RGAAGAAC 3' (r=A or G) or the decamers, AGGACAGAGC