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FLNC Rabbit Polyclonal Antibody, 50ul Virus Packaging RF1 and RF2

SKU: 75351084569

4.6
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FLNC Rabbit Polyclonal Antibody, 50ul Virus Packaging RF1 and RF2This gene encodes one of three related filamin genes specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N terminal filamentous actin binding domain a C terminal self association domain and a membrane glycoprotein binding domain. Two transcript variants

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Description

RF1 and RF2

A mutation in this gene has been shown to result in hypercatabolic hypoproteinemia

This protein and VP16 both bind to the same site on host cell factor C1

and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma

FLNC Rabbit Polyclonal Antibody, 50ul Virus Packaging RF1 and RF2This gene encodes one of three related filamin genes specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N terminal filamentous actin binding domain a C terminal self association domain and a membrane glycoprotein binding domain. Two transcript variants

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