Fra-1 Polyclonal Antibody, 50ul Adenovirus Packaging induction:By MYC overexpression in a

induction:By MYC overexpression in a concentration dependent manner in neuroblastoma cell line

resulting in a repulsive effect on glioma cell guidance in the developing brain

An important paralog of this gene is TCEAL4

also known as family 2 of ubiquitin carboxyl-terminal hydrolases

Fra-1 Polyclonal Antibody, 50ul Adenovirus Packaging induction:By MYC overexpression in aThe Fos gene family consists of 4 members: fOS, FOSB, FOSL1, and FOSL2. These genes encode leucine zipper proteins that can dimerize with proteins of the JUN family, thereby forming the transcription factor complex AP 1. As such, the FOS proteins have been implicated as regulators of cell proliferation, differentiation, and transformation. Several transcript variants encoding different isoforms have been found for FOSL1.