DSG4 Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) The encoded protein functions as

The encoded protein functions as a homodimer and interacts directly with both CSTF1 and CSTF2 in the CSTF complex

First isolated as a nuclear protein that binds to cAMP-response element binding protein (CREB)

Multiple pseudogenes have been identified for this gene

The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development

DSG4 Polyclonal Antibody, 20ul Centrifuge Tube (Bottle) The encoded protein functions asThis gene encodes a member of the desmoglein subgroup of desmosomal cadherins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a transmembrane component of desmosomes and may play a role in cell cell adhesion in epithelial cells. Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix, characterized by impaired hair growth.