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Survivin(Phospho Thr117) Polyclonal Antibody, 50ul Pipette Micro Tips Mutations in this gene are

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Survivin(Phospho Thr117) Polyclonal Antibody, 50ul Pipette Micro Tips Mutations in this gene areThis gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues.

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Description

Mutations in this gene are a cause of colorectal cancer (CRC)

The amyloid-like protein 1 is a membrane-associated glycoprotein that is cleaved by secretases in a manner similar to amyloid beta A4 precursor protein cleavage

This subunit is essential for the interaction between the 140 kDa subunit and the core complex that consists of the 36

This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer

Survivin(Phospho Thr117) Polyclonal Antibody, 50ul Pipette Micro Tips Mutations in this gene areThis gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues.

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